Metabolic imaging Metabolic imaging in dilated cardiomyopathy
نویسنده
چکیده
Cardiac metabolism is deranged in dilated cardiomyopathy (DCM). Phosphorus-31 (P) and hydrogen1 (H) magnetic resonance spectroscopy (MRS) allow for the non-invasive assessment of various aspects of cardiac metabolism, showing deranged cardiac energetics and lipid accumulation in DCM. In the future, MRS may become an important biomarker tool for monitoring the effects of novel heart-failure treatments in DCM. Heart Metab. 2011;49:13–16.
منابع مشابه
The value of myocardial perfusion imaging in differentiating between idiopathic dilated cardiomyopathy from the ischemic form [Persian]
Introduction: Differentiating between ischemic cardiomyopathy (ICM) and idiopathic dilated cardiomyopathy (IDCM) is important as coronary revascularization can improve prognosis in the ischemic subgroup. Due to inherent problems of coronary angiography in patients with depressed ejection fraction (EF) introducing a noninvasive tool to diagnose those who will benefit from angiography seems...
متن کاملMyocardial structural, perfusion, and metabolic correlates of left bundle branch block mechanical derangement in patients with dilated cardiomyopathy: a tagged cardiac magnetic resonance and positron emission tomography study.
BACKGROUND Left bundle branch block (LBBB) influences on regional left ventricular (LV) structure, perfusion, and metabolism have not yet been thoroughly investigated in dilated cardiomyopathy patients. METHODS AND RESULTS Eleven dilated cardiomyopathy patients with LBBB (mean+/-SD age, 62+/-11 years; LV ejection fraction, 35+/-8%) and 7 dilated cardiomyopathy patients without LBBB (mean+/-SD...
متن کاملCoronary artery or myocyte: wherein lies the diagnosis?
Patients who have left ventricular (LV) contractile dysfunction with dilatation of one or both ventricles receive the broad diagnosis of dilated cardiomyopathy (DCM), though further refinement is invariably required to guide appropriate therapy. Etiologic considerations span metabolic, toxic, infiltrative, structural, and congenital disorders, many of which may be apparent on initial history; h...
متن کاملThe Evolving Roles of Nuclear Cardiology
The use of cardiac imaging modalities has grown steadily, and cardiac nuclear studies constitute a large part of this number. Nuclear Cardiology is often mistakenly considered a synonym of myocardial perfusion imaging (MPI), but has broader applications, including metabolic imaging, innervation imaging, among other technologies. MPI has been a powerful diagnostic and prognostic tool in the asse...
متن کاملTracing ischemic memory by metabolic pathways: BMIPP and beyond
Myocardial ischemia (MI) resulting in infarction is an important cause of mortality and morbidity worldwide. Acute ischaemia rapidly impairs myocardial contractile function. Myocardial dysfunction persisting for several hours after transient non-lethal ischaemia, eventually resulting in full functional recovery is termed as myocardial stunning. Hibernation is now thought to be...
متن کامل